Long Island City (L.I.C.) is the westernmost residential and commercial neighborhood of the New York City borough of Queens. L.I.C. is noted for its rapid and ongoing residential growth and gentrification, its waterfront parks, and its thriving arts community. L.I.C. has among the highest concentration of art galleries, art institutions, and studio space of any neighborhood in New York City. It is bordered by Astoria to the north; the East River to the west; Hazen Street, 49th Street, and New Calvary Cemetery in Sunnyside to the east; and Newtown Creek—which separates Queens from Greenpoint, Brooklyn—to the south. It originally was the seat of government of the Town of Newtown, and remains the largest neighborhood in Queens. The area is part of Queens Community Board 1, located north of the Queensboro Bridge and Queens Plaza; it is also of Queens Community Board 2 to the south.

Long Island City is the eastern terminus of the Queensboro Bridge, also known as the 59th Street Bridge, which is the only non-toll automotive route connecting Queens and Manhattan.